Propranolol Hydrochloride
Product Description
2-Deoxy-D-ribose is a naturally occurring deoxy sugar derived from D-ribose, distinguished by the absence of an oxygen atom at the 2-carbon position. It is an aldopentose and a critical structural component of DNA, forming part of its sugar-phosphate backbone. It participates in several biological functions, including cellular metabolism and energy production, and is commonly found as a white crystalline powder soluble in water, ethanol, and DMSO.
Product Use & Characteristics
Chemical Identity: A deoxy sugar (missing an oxygen atom at carbon-2), aldopentose, and component of DNA.
Biological Functions:
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Fundamental to DNA structure.
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Involved in energy metabolism (notably ATP-related pathways).
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Found in multiple organisms as a metabolic intermediate.
Applications:
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Used in supplements for energy and recovery.
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Researched for heart health (e.g., improving myocardial metabolism).
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Tool in cellular metabolism studies (e.g., chronic fatigue syndrome).
Physical Properties:
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White/off-white crystalline powder.
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Soluble in water, ethanol, and DMSO.
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Melting point: ~89–90°C.
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Exhibits optical activity.
Biomedical Research:
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Promotes angiogenesis (formation of blood vessels), aiding in wound healing.
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Combined with lidocaine in hydrogel to relieve pain and enhance healing in wound models.
Toxicology and Cellular Effects:
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Induces ferroptosis (a type of cell death) in renal tubular epithelial cells via degradation of the xCT protein by the ubiquitin-proteasome system.
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Reduces intracellular cystine and glutathione, promoting oxidative damage.
Polymer Chemistry:
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Source for bio-based aliphatic polycarbonates via ring-opening polymerization.
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Used in developing biodegradable, biocompatible polymers from sugars and CO₂.