N-Methyltaurine Sodium Salt

CAS Number 4316-74-9
Molecular Formula C₃H₈NNaO₃S
Molecular Weight 161.16 g/mol
Purity ≥99.5%
Appearance White crystalline solid

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Product Description

N-Methyltaurine Sodium Salt, also known as Sodium 2-(methylamino)ethanesulfonate, is an organic sulfonic acid salt. Its structure features a two-carbon ethylene backbone with a secondary (methylamino) group attached to one end and a sulfonate group at the other, balanced by a sodium cation. This polar, water-soluble molecule is used in surfactants, detergent formulations, and biochemical research as a zwitterionic buffer component or intermediate. It is also recognized as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) when formulated to be non-irritating.

Packaging

  • Common Sizes: 1kg aluminum foil bags, 25kg plastic drums.

Synthesis Methods

  • Common Synthesis Methods:

    • Reacting ethylenediamine with sodium ethenesulfonate.

    • Heating aqueous sodium 2-hydroxyethanesulfonate with amine starting materials (e.g., methylamine) in an autoclave under controlled conditions.

    • Reacting N-methyltaurine with an alkali like sodium hydroxide.

    • The reaction of sodium isethionate with methylamine under high temperature and pressure.

    • Reacting sodium taurinate with formaldehyde, followed by hydrogenation.

Uses

  • Pharmaceuticals: Used as a pharmaceutical intermediate in the production of various fine chemical products.

  • Cosmetics: Used in personal care products like shampoos, body washes, and soaps due to its amphiphilic properties.

  • Food & Beverage: Used as a component in food additives.

  • Agriculture: Used in agricultural formulations.

  • Animal Feed: Used in animal feed formulations.

  • Scientific Research: Used as an intermediate in synthesizing water-soluble polythiophene derivatives for conductive materials. It also serves in biological studies, such as producing Gemini surfactants, analyzing enzyme kinetics, and studying protein interactions.

  • Material Science: Used as a monomer in the synthesis of specialized polymers, such as water-soluble polythiophene derivatives, which are used in electronics and other conductive materials.

  • Industrial Uses: Used as a polymerization monomer, solvent, antifreeze, and in the production of surfactants and surface-active agents.

Basic Information

  • Chemical Name: Sodium 2-(methylamino)ethanesulfonate

  • Synonyms: N-Methyltaurine Sodium Salt, Sodium N-methyltaurinate

  • Molecular Formula: C₃H₈NNaO₃S

  • Molecular Weight: 161.16 g/mol

  • CAS Number: 4316-74-9

Physical and Chemical Properties

  • Appearance: Typically a colorless or pale yellow liquid in aqueous solution, or a white solid in anhydrous form.

  • Solubility: Highly soluble in water (410 g/L at 20°C), slightly soluble in methanol and DMSO.

  • Boiling Point: 493.73°C at 101,325 Pa.

  • Density: 1.21 g/cm³.

  • pKa: 8.66 at 20°C (effective as a buffer in neutral to alkaline pH range).

  • Stability: Stable under normal conditions but should be stored in a cool, dry, ventilated area away from incompatible substances.

Safety and Handling

  • Hazard Classification: Classified as a dangerous substance (GHS05 - Corrosive), with potential to cause severe skin burns and serious eye damage.

  • Personal Protective Equipment (PPE): Wear appropriate PPE, including protective gloves, eye protection, and a respirator if there is a risk of inhalation.

  • First Aid:

    • Inhalation: Move to fresh air. If breathing is difficult, provide oxygen.

    • Skin Contact: Rinse affected area with plenty of water. Remove contaminated clothing.

    • Eye Contact: Rinse eyes with plenty of water for at least 15 minutes. Remove contact lenses if present.

    • Ingestion: Rinse mouth. Do not induce vomiting. Seek medical attention.

  • Storage: Store in a cool, dark place. Keep containers tightly closed. Protect from moisture and incompatible substances.

Regulatory Information

  • Cosmetic Ingredient Review (CIR): The CIR Expert Panel concluded that Sodium Methyltaurate is safe in cosmetics when formulated to be non-irritating.

  • Toxic Substance Control Act (TSCA): Listed on the TSCA Inventory.

  • International Inventories: Listed on various international chemical inventories, including DSL (Canada) and TSCA (USA).

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