Epinephrine bitartrate CAS No. 51-42-3

Product Description

Epinephrine bitartrate, also known as adrenaline bitartrate, is the bitartrate salt of epinephrine—a potent, direct-acting sympathomimetic amine used primarily in emergency medical situations. It is widely applied in the treatment of severe allergic reactions (anaphylaxis), asthma attacks, and cardiac arrest due to its ability to stimulate both alpha- and beta-adrenergic receptors, leading to critical physiological responses such as vasoconstriction and bronchodilation.

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Product Use & Characteristics

• Mechanism of Action: Acts on both alpha- and beta-adrenergic receptors; alpha stimulation causes vasoconstriction, while beta stimulation induces bronchodilation and cardiac stimulation.

• Physiological Effects: Increases heart rate, myocardial contractility, bronchodilation, vasoconstriction, vasodilation, tocolysis, and renin release. Also promotes glycogenolysis and lipolysis.

• Medical Uses: Treatment of asthma, anaphylaxis, cardiac failure, and to delay the absorption of local anesthetics.

• Chemical Properties:

  • Appearance: White to greyish-white crystalline powder

  • Solubility: Soluble in water (22.9 mg/mL), slightly soluble in ethanol

  • Molecular Weight: 333.29 g/mol

  • Formula: C₉H₁₃NO₃·C₄H₆O₆

  • CAS Number: 51-42-3

• Pharmaceutical Research: Included in advanced spectrophotometric methods for simultaneous analysis with Articaine Hydrochloride, especially for formulations with extreme concentration ratios (4000:1).

• Green Chemistry: Recent studies emphasized eco-friendly and non-toxic analytical techniques for detecting epinephrine bitartrate, adhering to green chemistry principles.

Why us!

Sigma Chemical Group is a major chemical enterprise headquartered in Hangzhou, Zhejiang Province, with a diversified portfolio of subsidiaries including Qingdao Sigma Chemical Co., Ltd., Henan Sigma Biotechnology Co., Ltd., Nanchang Sigma Chemical Co., Ltd., and Jinan Sigma Chemical Co., Ltd. Established on January 16, 2017, Qingdao Sigma Chemical Co., Ltd. operates as a micro-sized chemical product wholesaler with a registered capital of RMB 100,000. Led by legal representative Yang Yuwen and based at 2-1-2301, Jiahe Xinxing, No. 130 Shandong Road, Shibei District, Qingdao, the company’s operations span chemicals, machinery equipment, and import-export services. Henan Sigma Biotechnology Co., Ltd., located in Dongmafang, Muye District, Xinxiang City, Henan Province, specializes in the sales of pesticides, pharmaceuticals, veterinary drugs, and mixed feed additive series, including products like adenine, florfenicol injection, carbasalate calcium soluble powder, and cefotaxime sodium chloride injection. Guided by a win-win and innovative business philosophy, the company employs a modern management approach and customer-centric service, upholding integrity, diligence, and a commitment to quality, thereby earning customer trust through diverse product offerings and competitive pricing. Nanchang Sigma Chemical Co., Ltd., situated in Nanchang, Jiangxi Province, is dedicated to producing high-purity plant extracts, emphasizing eco-friendly, non-toxic chemical raw materials that generate no environmental pollutants. Jinan Sigma Chemical Co., Ltd., located in Jinan, the capital of Shandong Province known as the "City of Springs," focuses on manufacturing active pharmaceutical ingredients (APIs) and pharmaceutical intermediates. The company maintains long-term industry-academia-research collaborations with Shandong University and Qilu University of Technology, continuously enhancing R&D investments to drive innovation and growth.